Bone Resorption (Bone Loss) – Causes, Symptoms and Treatment

Bone Resorption

Table of contents

What Is Bone Resorption?

Bone resorption is the process in which bone tissue is broken down and minerals such as calcium are released into the bloodstream. While this is a natural part of bone remodeling, excessive bone resorption leads to decreased bone density and increased fracture risk.

In healthy individuals, bone formation and bone breakdown remain balanced. When this balance shifts toward destruction, bone loss occurs.

What Causes Bone Resorption?

Several medical conditions and lifestyle factors can accelerate bone loss:

1️⃣ Osteoporosis

The most common cause of systemic bone loss. It is particularly prevalent in postmenopausal women.

2️⃣ Hormonal Imbalances

  • Estrogen deficiency

  • Hyperthyroidism

  • Parathyroid gland disorders

3️⃣ Periodontitis

Advanced gum disease may cause localized bone resorption in the jaw.

4️⃣ Trauma or Infections

Bone fractures, surgeries, or infections can trigger bone breakdown.

5️⃣ Long-term Corticosteroid Use

Symptoms of Bone Loss

Early stages may not present symptoms. In advanced cases:

  • Frequent fractures

  • Loss of height

  • Back pain

  • Postural changes

  • Tooth loss (if jawbone is affected)

Diagnosis

  • Bone Mineral Density (DEXA scan)

  • Blood tests (calcium, vitamin D, hormone levels)

  • Radiological imaging

Early diagnosis significantly reduces fracture risk.

Treatment Options

Treatment depends on the underlying cause.

✔ Calcium and Vitamin D supplementation
✔ Bisphosphonate therapy
✔ Hormone therapy
✔ Weight-bearing exercise
✔ Lifestyle modifications

In severe cases, surgical intervention may be required.

Prevention

  • Regular bone density screenings

  • Adequate calcium and vitamin D intake

  • Active lifestyle

  • Avoid smoking and excessive alcohol

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